Muscle pains and aches and can involve more than one muscle, in addition to ligaments, tendons, and fascia, the soft tissues that connect muscles, bones, and organs. Muscle pain results from tension, overuse, or muscle injury from exercise or physically demanding work. The pain involves specific muscles and begins during or immediately following the activity. Muscle pain also can signify conditions affecting the entire body, such as infections like the flu and disorders that affect conne